NCLEX pharmacology practice question on Insulin for the patient with diabetes mellitus. This NCLEX-style question will test your knowledge about Insulin Lispro (Humalog) and wants to know when the patient is at most risk for hypoglycemia based on the time you administered the medication.

On the NCLEX exam, it is inevitable you will receive pharmacology type questions. This particular NCLEX practice question will require you to determine what type of insulin Lispro is (rapid, short, intermediate, or long-acting) and when a patient is at most risk for hypoglycemia (onset, peak, duration).

This video is part of a weekly NCLEX review series where I will be going over NCLEX-style questions with you. I will be helping you analyze and breakdown each question, and walk you through how to select the correct option.

NCLEX questions require critical thinking and you must know how to use your nursing knowledge to gather the facts and analyze what the question is asking.

NCLEX Pharmacology Practice Question on Insulin:

Your patient’s blood glucose level is 215 mg/dL. The patient is about to eat lunch. Per sliding scale, you administer 4 units of Insulin Lispro (Humalog) subcutaneously at 1130. As the nurse, you know the patient is most at risk for hypoglycemia at what time?

A. 1145
B. 1230
C. 1430
D. 1630

Watch the video for the correct answer and rationale.

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Antidiabetic drugs are medications used to treat diabetes mellitus by lowering blood glucose levels. With the exception of insulin, exenatide, liraglutide and pramlintide, all are administered orally and are thus also called oral hypoglycemic agents. This pharmacology lecture covers topics such as pathophysiology of diabetes mellitus type 1 & type 2, hyperglycemia, hypoglycemia, insulin production, pancreatic beta & alpha cells, glycogen, glucagon, glucose function; mechanism of action of glucose-lowering drugs; rapid, short, intermediate, long -acting insulin analogs, synthetic amylin, incretin mimetics, DPP-4 inhibitors, sulfonylureas, glinides, biguanides, thiazolidinediones, sodium-glucose cotransporter-2 inhibitors, and alpha-glucosidase inhibitors. Drugs mentioned include insulins Lispro, Aspart, Glulisine, Regular, NPH (isophane), Detemir, Glargine, Degludec; Pramlintide; Exenatide, Liraglutide; Alogliptin, Linagliptin, Saxagliptin, Sitagliptin; Glimepiride, Glyburide, Glipizide; Nateglinide, Repaglinide; Metformin; Pioglitazone, Rosiglitazone; Canagliflozin, Dapagliflozin; Acarbose, and Miglitol.

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