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Robert Lustig – What is Metabolic Syndrome Anyway?
From the JumpstartMD Weight of the Nation Conference 2018
JumpstartMD is a medical practice dedicated to pre-emptive medicine through lifestyle changes and healthy, sustainable weight loss. Personalized program based on proven nutritional science, one-on-one lifestyle counseling and real, fresh food. Founded by Stanford trained physicians and board-certified Diplomates of the American Board of Obesity Medicine. PPO, HSA and FSA reimbursement support provided to patients.
With a strong commitment to reducing the quality and quantity of carbohydrates consumed, the stigmata of metabolic syndrome and fatty liver disease can reverse even before weight loss although much more dramatically in combination. For example, with as little as 10 percent weight loss, which 95 percent of our clients achieve at 6 months, NAFLD (Nonalcoholic fatty liver disease) is often reversed. Cost wise, patients without NAFLD show a 26 percent lowering in their health costs over 5 years.
But more importantly, with pre-emptive elimination of fatty liver disease, there’s no need to see the transplant surgeon. The prescription is simply guiding and supporting people toward healthy lifestyle changes that work to preempt diseases like fatty liver disease or the others that go along with it: diabetes, heart attacks, strokes, metabolic syndrome, various cancers, and arguably dementia. The improvements are dramatic, transformational, and utterly sensible.
JumpstartMD has convenient weight loss centers throughout the San Francisco Bay Area, from Marin to Monterey and San Francisco to Pleasanton. Our offices have a range of services and hours to help support your goals and lifestyle.
More at www.jumpstartmd.com or (855) JUMPSTART. Video Rating: / 5
Robert H. Lustig, M.D., M.S.L. is Professor emeritus of Pediatrics, Division of Endocrinology at the University of California, San Francisco (UCSF). He specialises in the field of neuroendocrinology, with an emphasis on the regulation of energy balance by the central nervous system. His research and clinical practice has focused on childhood obesity and diabetes. Dr. Lustig holds a Bachelor’s in Science from MIT, a Doctorate in Medicine from Cornell University. Medical College, and a Master’s of Studies in Law from U.C. Hastings College of the Law.
Dr. Lustig has fostered a global discussion of metabolic health and nutrition, exposing some of the leading myths that underlie the current pandemic of diet-related disease. He believes the food business, by pushing processed food loaded with sugar, has hacked our bodies and minds to pursue pleasure instead of happiness; fostering today’s epidemics of addiction and depression. Yet by focusing on real food, we can beat the odds against sugar, processed food, obesity, and disease.
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View episode show notes here: https://bit.ly/3ugel18
Rick Johnson, Professor of Nephrology at the University of Colorado and a previous guest on The Drive, returns for a follow-up about unique features of fructose metabolism, and how this system that aided the survival of human ancestors has become potentially hazardous based on our culture’s dietary norms. In this episode, Rick explains how the body can generate fructose from glucose and how circulating glucose and salt levels can activate this conversion. He discusses the decline in metabolic flexibility associated with aging, as well as how factors such as sugar intake or menopause-associated hormone changes can alter responses to sugar across a lifetime. In addition, Rick lays out strategies for combating the development of metabolic illness using dietary changes and pharmaceutical therapies, and he discusses the impact of fructose metabolism and uric acid on kidney function and blood pressure. He concludes with a discussion of vasopressin, a hormone that facilitates fructose’s effects on weight gain and insulin resistance.
We discuss:
00:00:00 – Intro
00:00:10 – Unique features of fructose metabolism and why it matters
00:09:00 – A primer on fructose metabolism and uric acid
00:21:04 – Endogenous fructose production, the polyol pathway, and the effect of non-fructose sugars
00:28:20 – Findings from animal studies of glucose and fructose consumption
00:45:06 – What calorie-controlled studies say about the claim that a “calorie is a calorie”
00:56:45 – Implications for aging and disease
01:08:58 – Impact of endogenous fructose production on obesity and metabolic syndrome
01:12:43 – Why vulnerability to the negative effects of sugar increases with age and menopause
01:26:43 – Dietary strategies to reduce the negative impact of fructose
01:43:56 – The role of hypertension in chronic disease and tips for lowering blood pressure
01:54:16 – The impact of fructose and uric acid on kidney function and blood pressure
02:04:50 – The potential role of sodium in hypertension, obesity, and metabolic syndrome
02:11:18 – The role of vasopressin in metabolic disease
——–
About:
The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 35 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more.
Peter is a physician focusing on the applied science of longevity. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease), while simultaneously improving healthspan (quality of life).
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Dr. Robert Lustig is an endocrinologist and professor of pediatrics in the Division of Endocrinology at the University of California-San Francisco. In this video, he sits down with CrossFit’s Rory McKernan to explain sugar’s toxicity, outline the stakes of sugar consumption and offer suggestions for addressing the ongoing sugar crisis.
“Sugar is toxic,” Lustig explains. “It proffers a set of biochemical alterations that are detrimental to human health—unrelated to its calories.”
In this way, Lustig says, sugar “is very much like alcohol,” and chronic metabolic diseases associated with alcohol are becoming prevalent in children with high-sugar diets.
When asked about the state of pediatric medicine in the United States, Lustig says, “We have a problem.”
Because the food industry has negatively influenced nutrition science for the last 45 years, many people still abide by the mistaken belief that a healthy diet is attained by regulating calories and saturated fat. This misconception has led to a rise in chronic metabolic diseases such as Type 2 diabetes in adult and youth populations.
People who believe they are making healthy choices and avoiding sugar are nevertheless affected by the crisis.
“Even though you might not be sick,” Lustig says, “society is.”
In the final third of the video, Lustig outlines the necessary steps for enacting a societal intervention. These steps include educating the public, approaching sugar as an addictive substance and calling Type 2 diabetes what it is: “processed food disease.”
The CrossFit Journal — (http://journal.crossfit.com)
The CrossFit Games® – The Sport of Fitness™
The Fittest On Earth™ Video Rating: / 5
Research is telling us that those with Type 2 diabetes don’t need to be testing for blood glucose levels at home and that doing so is a waste of money and a strain on the health care system.
Other HCT Episodes on Diabetes:
1. YMCA and the Diabetes Prevention Program: https://www.youtube.com/watch?v=mR77alFcekw
2. The Effectiveness of Screening and Treating Diabetes: https://www.youtube.com/watch?v=kLCI58lbqcE
Be sure to check out our podcast! https://www.youtube.com/watch?v=3cXfQgdsKps
Healthcare Triage Links:
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2. Check out our Facebook page: http://goo.gl/LnOq5z
3. We still have merchandise available at http://www.hctmerch.com
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