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An international collaboration co-led by researchers at the Walter and Eliza Hall Institute has made a discovery that could enable therapeutic insulins to be made more effective than they currently are.
The findings will help to improve treatments for diabetes, a disease that impacts the lives of millions of people worldwide.
Published in Nature Communications, the study reveals the first definitive 3D image of how insulin successfully interacts with its receptor, a ‘gatekeeper’ for transmitting information into cells, in a process that is crucial for instructing cells to lower blood sugar levels in the body.
Understanding exactly what this process looks like can inform the design of faster-acting and longer-lasting insulin therapies.
Read more: https://www.wehi.edu.au/news/insulin-discovery-game-changer-improving-diabetes-treatments Video Rating: / 5
Before people develop Type 2 diabetes, they almost always have “pre-diabetes” — blood glucose levels that are higher than normal, but not high enough to be diagnosed as diabetes. The good news is there are things you can do to prevent or delay the development of full-blown disease.
Stan Hilman was happily eating his way through life until he learned it was jeopardizing his health.
“I brought it upon myself by eating the wrong stuff and never thinking that this would catch up with me. But it does,” says Hilman.
Stan is hardly the only one. It’s estimated 79 million people, or 35 percent of the U.S. population have pre-diabetes. People poised on the brink of full-blown disease are fueling the diabetes epidemic.
“Diabetes is expected to double, as far as the prevalence, by 2050,” says Sharon Krispinski, a diabetes educator for Lee Health Solutions.
About 70 percent of pre-diabetics will eventually develop Type 2 diabetes. But new research suggests they may be able to detour the disease process through aggressive life-style changes.
“It’s healthy eating; it’s more high fiber foods, more non-starchy vegetables, lean protein. And it’s exercise,” says Krispinski.
“When they told me that I was pre-diabetic, I attended classes with Lee Memorial and found out what things are proper to eat and things to stay away from,” says Hilman.
“We emphasize to our patients that even with a modest weight loss, a 5 to 10 percent weight loss, they can significantly improve their blood sugar,” says Krispinski.
Doctors can use three different tests to tell if you have pre-diabetes: the AIC test, the fasting plasma glucose test (FPG) or oral glucose tolerance test (OGTT). It put Stan on a path to wellness.
“I want to be healthy,” says Hilman.
View More Health Matters video segments at leememorial.org/healthmatters/
Lee Memorial Health System in Fort Myers, FL is the largest network of medical care facilities in Southwest Florida and is highly respected for its expertise, innovation and quality of care. For nearly a century, we’ve been providing our community with everything from primary care treatment to highly specialized care services and robotic assisted surgeries.
To learn more visit: http://www.AnimatedDiabetesPatient.com
Experts provide simple, understandable explanations about the different oral medications that are available for the treatment of type 2 diabetes. They discuss the major classes of drugs and modes of action.
To learn more visit: http://www.AnimatedDiabetesPatient.com
Diet and exercise are the most effective treatments for type 2 diabetes – in most cases. All other treatments including pills and insulin and other injectables have a supporting role and should be used in conjunction to diet and exercise. Medications prescribed for type 2 diabetes require that patients also adhere to diet and exercise. Video Rating: / 5
Learn more at: http://www.AnimatedDiabetesPatient.com
The goal of Type 2 Diabetes treatment is to safely keep blood glucose within the normal range. When diet and exercise fail to provide patient benefits, medical management of diabetes is warranted. Various medications for controlling blood sugar are briefly explained. A self-management plan should be part of every patient’s strategy with regular doctor visits. Video Rating: / 5
